Cancer is a disease of uncontrolled cell division, favouring survival in poor environments. These microenvironments often have a limited nutrient and energy supply, forcing cancer cells to divide under stress. The mechanical force required for cytokinesis is provided by the Contractile Actomyosin Ring (CAR), however, the regulation of CAR constriction (therefore cell division) in response to environmental stress, is unknown. We utilised the model organism Schizosaccharomyces pombe to analyse cytokinesis following various environmental stresses that result in AMPK activation, using live-cell imaging. We demonstrate that salt stress induces a significant delay to cell division, as the time to complete cytokinesis increased from 45 to 120 minutes following high salt exposure. Moreover, we present a novel requirement for AMPK in post salt-stress cell division, as cells lacking AMPK were unable to initiate CAR constriction, thus failing cytokinesis. We found that AMPK was not required for cytokinesis under numerous environmental stresses that activate AMPK, where the stress did not promote a delay to cell division in wild-type cells. This demonstrates that AMPK only becomes essential for cytokinesis following environmental stress that blocks CAR constriction. Additionally, preliminary observations assessing post-stress cytokinesis in human cells suggests this process may be conserved between species. We provide evidence of an environment-dependent regulation of cytokinesis by AMPK, further expanding the breadth of AMPK signalling throughout the cell cycle. By achieving greater understanding of cytokinesis regulation following environmental stress, a scenario seen frequently in cancer cells, therapeutic targets can be established to reduce cancer proliferation in poor environments.